STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Rho guanine nucleotide exchange factor 4. (1876 aa)    
Predicted Functional Partners:
APC
Adenomatous polyposis coli protein isoform X10.
   
 0.997
APC2
APC2 isoform 1.
   
 0.963
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
    
 0.908
SPATA13
Spermatogenesis-associated protein 13 isoform X4.
    
 
0.907
RHOA
Ras homolog family member A.
    
 0.645
ENSPTRP00000066583
annotation not available
    
 0.606
ENSPTRP00000081694
annotation not available
    
 0.606
IQGAP1
IQ motif containing GTPase activating protein 1.
    
 
 0.566
KIFAP3
Kinesin-associated protein 3.
   
  
 0.554
GABRA2
Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.542
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.