STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LY75LY75-CD302 isoform 2. (1722 aa)    
Predicted Functional Partners:
ITGB6
ITGB6 isoform 3.
 
 
 0.863
GRB14
Growth factor receptor-bound protein 14.
      
 0.822
CD302
CD302 antigen isoform X1.
    
 
0.785
CLEC4A
C-type lectin domain family 4 member A.
   
  
 0.573
ITGAX
Integrin subunit alpha X; Belongs to the integrin alpha chain family.
   
 
 0.534
CLEC9A
CLEC9A isoform 1.
   
  
 0.519
CD207
CD207 isoform 1.
   
  
 0.516
CLEC4M
C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).
   
  
0.500
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.480
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
   
 
 0.478
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.