STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)    
Predicted Functional Partners:
HAMP
Hepcidin antimicrobial peptide.
    
 
 0.990
HEPH
HEPH isoform 1; Belongs to the multicopper oxidase family.
    
 0.965
CP
CP isoform 1; Belongs to the multicopper oxidase family.
    
 0.953
ENSPTRP00000078404
annotation not available
      
 0.814
SLC11A2
SLC11A2 isoform 1.
      
 0.795
TFR2
Transferrin receptor 2.
      
 0.788
HFE
Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
      
 0.755
CYBRD1
Cytochrome b reductase 1.
      
 0.745
PCBP2
Poly(rC) binding protein 2.
      
 0.720
TFRC
Transferrin receptor (P90, CD71).
      
 0.699
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.