STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)    
Predicted Functional Partners:
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing.
    
 0.999
VAC14
VAC14 component of PIKFYVE complex.
    
 0.998
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.959
MTMR2
MTMR2 isoform 3.
     
 0.943
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
     
 0.937
MTM1
MTM1 isoform 1.
     
 0.936
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase, type II, beta.
     
0.929
SACM1L
SAC1 like phosphatidylinositide phosphatase.
    
 0.929
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.928
PI4KA
PI4KA isoform 3; Belongs to the PI3/PI4-kinase family.
     
 0.925
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.