STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NGEFNeuronal guanine nucleotide exchange factor. (710 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
    
 0.978
EPHA4
EPH receptor A4.
    
 0.976
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
    
 0.965
EPHA1
EPH receptor A1.
    
 0.961
EPHA5
EPH receptor A5.
    
 0.955
EPHB2
EPH receptor B2.
    
 0.950
EPHA3
EPH receptor A3.
    
 0.934
EPHA2
EPH receptor A2.
    
 0.931
EPHB1
EPH receptor B1.
    
 0.931
EPHA6
EPH receptor A6.
    
 0.930
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.