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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1R7Protein phosphatase 1, regulatory (Inhibitor) subunit 7. (376 aa)    
Predicted Functional Partners:
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.927
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.921
ENSPTRP00000069894
annotation not available
   
 0.920
PPP1CC-2
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.920
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.920
RSU1
Ras suppressor protein 1.
  
   
 0.842
TTC1
Tetratricopeptide repeat domain 1.
   
    0.801
PPP1R11
E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1.
   
 
 0.801
PPP1R16B
Protein phosphatase 1 regulatory subunit 16B.
    
 0.754
ENSPTRP00000069721
annotation not available
   
 
 0.751
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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