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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family. (206 aa)    
Predicted Functional Partners:
STX1A
STX1A isoform 3; Belongs to the syntaxin family.
   
 0.999
CPLX1
CPLX1 isoform 1.
   
 0.998
STX1A-2
Syntaxin 1A.
   
 0.998
SYT1
Synaptotagmin 1.
   
 0.997
VAMP2
VAMP2 isoform 3.
   
 0.997
STX3
STX3 isoform 2; Belongs to the syntaxin family.
   
 0.990
VAMP1
Vesicle associated membrane protein 1.
   
 0.986
VAMP3
Vesicle-associated membrane protein 3 (Cellubrevin).
   
 0.985
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.984
STX1B
STX1B isoform 1; Belongs to the syntaxin family.
   
 0.983
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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