STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CST7CST7 isoform 1. (145 aa)    
Predicted Functional Partners:
GZF1
GDNF inducible zinc finger protein 1.
      
 0.889
CST9L
CST9L isoform 1.
   
 
 0.881
NXT1
Nuclear transport factor 2 like export factor 1.
      
 0.850
ACSS1
Acetyl-coenzyme A synthetase.
      
 0.833
MATK
Tyrosine-protein kinase.
   
 
 0.820
NKG7
NKG7 isoform 2.
   
  
 0.738
ENSPTRP00000079860
annotation not available
   
 
 0.663
SPON2
Spondin 2, extracellular matrix protein.
      
 0.607
TMEM119
Transmembrane protein 119.
      
 0.570
NPC2
NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...]
   
  
 0.521
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.