STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB123Beta-defensin 123; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)    
Predicted Functional Partners:
TFAP2D
Transcription factor AP-2 delta.
      
 0.742
ZCCHC3
Zinc finger, CCHC domain containing 3.
      
 0.742
SPATA4
Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.
      
 0.638
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (Lysophosphatidic acid acyltransferase, epsilon).
      
 0.628
DEFB119
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.588
DEFB105A
Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.
     
 0.546
DEFB124
Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.529
TNP1
Spermatid nuclear transition protein 1.
  
     0.518
DEFB115
DEFB115 isoform 1.
     
 0.510
DEFB113
Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.497
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.