STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCKTyrosine-protein kinase. (526 aa)    
Predicted Functional Partners:
LYN
Tyrosine-protein kinase.
  
0.979
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.977
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.965
SHC1
SHC (Src homology 2 domain containing) transforming protein 1.
   
 0.962
ITK
Tyrosine-protein kinase.
  
0.961
PIK3R1
Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha).
    
 0.961
PTK2B
PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.957
ELMO1
Engulfment and cell motility 1.
    
 0.952
PIK3R2
Phosphoinositide-3-kinase, regulatory subunit 2 (Beta).
    
 0.945
SHC3
SHC3 isoform 2.
   
 0.945
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.