EIF2S2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF1AX	EIF2S1	ENSPTRP00000037252	ENSPTRP00000010961	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa.	0.947
EIF1AX	EIF2S2	ENSPTRP00000037252	ENSPTRP00000022998	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa.	0.926
EIF1AX	EIF2S3	ENSPTRP00000037252	ENSPTRP00000063017	Eukaryotic translation initiation factor 1A X-linked.	EIF2S3 isoform 3.	0.832
EIF1AX	EIF2S3B	ENSPTRP00000037252	ENSPTRP00000054742	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 2 subunit gamma B.	0.781
EIF1AX	EIF3G	ENSPTRP00000037252	ENSPTRP00000017818	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.815
EIF1AX	EIF3I	ENSPTRP00000037252	ENSPTRP00000000837	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.757
EIF1AX	EIF3J	ENSPTRP00000037252	ENSPTRP00000078279	Eukaryotic translation initiation factor 1A X-linked.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.773
EIF1AX	LOC455519	ENSPTRP00000037252	ENSPTRP00000069007	Eukaryotic translation initiation factor 1A X-linked.	EIF2S3 isoform 1.	0.830
EIF1AY	EIF2S1	ENSPTRP00000038797	ENSPTRP00000010961	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa.	0.947
EIF1AY	EIF2S2	ENSPTRP00000038797	ENSPTRP00000022998	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa.	0.926
EIF1AY	EIF2S3	ENSPTRP00000038797	ENSPTRP00000063017	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	EIF2S3 isoform 3.	0.830
EIF1AY	EIF2S3B	ENSPTRP00000038797	ENSPTRP00000054742	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 2 subunit gamma B.	0.781
EIF1AY	EIF3G	ENSPTRP00000038797	ENSPTRP00000017818	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.815
EIF1AY	EIF3I	ENSPTRP00000038797	ENSPTRP00000000837	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.757
EIF1AY	EIF3J	ENSPTRP00000038797	ENSPTRP00000078279	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.773
EIF1AY	LOC455519	ENSPTRP00000038797	ENSPTRP00000069007	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family.	EIF2S3 isoform 1.	0.830
EIF2B5	EIF2S1	ENSPTRP00000026977	ENSPTRP00000010961	Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa.	Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa.	0.947
EIF2B5	EIF2S2	ENSPTRP00000026977	ENSPTRP00000022998	Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa.	Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa.	0.950
EIF2B5	EIF2S3	ENSPTRP00000026977	ENSPTRP00000063017	Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa.	EIF2S3 isoform 3.	0.933
EIF2B5	EIF2S3B	ENSPTRP00000026977	ENSPTRP00000054742	Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa.	Eukaryotic translation initiation factor 2 subunit gamma B.	0.909