STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC736246Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)    
Predicted Functional Partners:
ANAPC11
Anaphase promoting complex subunit 11.
   
 0.953
CDC20
Cell division cycle 20 homolog.
   
 0.950
LOC737111
Cell division cycle protein 20 homolog pseudogene.
   
 0.950
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.921
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.914
CCNA2
CCNA2 isoform 1; Belongs to the cyclin family.
   
 0.900
CCNB2
CCNB2 isoform 1; Belongs to the cyclin family.
   
 0.877
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 0.872
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.868
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.868
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.