CHRNA4 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRNA3	CHRNA4	ENSPTRP00000078686	ENSPTRP00000088336	Cholinergic receptor nicotinic alpha 3 subunit.	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	0.965
CHRNA3	CHRNA5	ENSPTRP00000078686	ENSPTRP00000012554	Cholinergic receptor nicotinic alpha 3 subunit.	Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.992
CHRNA3	CHRNA6	ENSPTRP00000078686	ENSPTRP00000034613	Cholinergic receptor nicotinic alpha 3 subunit.	Neuronal acetylcholine receptor subunit alpha-6; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.983
CHRNA3	CHRNA7	ENSPTRP00000078686	ENSPTRP00000011728	Cholinergic receptor nicotinic alpha 3 subunit.	CHRNA7 isoform 7.	0.957
CHRNA3	CHRNB1	ENSPTRP00000078686	ENSPTRP00000014815	Cholinergic receptor nicotinic alpha 3 subunit.	Cholinergic receptor, nicotinic, beta 1 (Muscle).	0.953
CHRNA3	CHRNB2	ENSPTRP00000078686	ENSPTRP00000002339	Cholinergic receptor nicotinic alpha 3 subunit.	CHRNB2 isoform 2.	0.989
CHRNA3	CHRNB3	ENSPTRP00000078686	ENSPTRP00000054732	Cholinergic receptor nicotinic alpha 3 subunit.	Neuronal acetylcholine receptor subunit beta-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.985
CHRNA3	CHRNB4	ENSPTRP00000078686	ENSPTRP00000012561	Cholinergic receptor nicotinic alpha 3 subunit.	Cholinergic receptor nicotinic beta 4 subunit.	0.996
CHRNA3	CHRNE	ENSPTRP00000078686	ENSPTRP00000014702	Cholinergic receptor nicotinic alpha 3 subunit.	Cholinergic receptor nicotinic epsilon subunit.	0.953
CHRNA3	CHRNG	ENSPTRP00000078686	ENSPTRP00000046107	Cholinergic receptor nicotinic alpha 3 subunit.	Cholinergic receptor nicotinic gamma subunit.	0.953
CHRNA4	CHRNA3	ENSPTRP00000088336	ENSPTRP00000078686	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Cholinergic receptor nicotinic alpha 3 subunit.	0.965
CHRNA4	CHRNA5	ENSPTRP00000088336	ENSPTRP00000012554	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.991
CHRNA4	CHRNA6	ENSPTRP00000088336	ENSPTRP00000034613	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Neuronal acetylcholine receptor subunit alpha-6; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.994
CHRNA4	CHRNA7	ENSPTRP00000088336	ENSPTRP00000011728	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	CHRNA7 isoform 7.	0.967
CHRNA4	CHRNB1	ENSPTRP00000088336	ENSPTRP00000014815	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Cholinergic receptor, nicotinic, beta 1 (Muscle).	0.965
CHRNA4	CHRNB2	ENSPTRP00000088336	ENSPTRP00000002339	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	CHRNB2 isoform 2.	0.997
CHRNA4	CHRNB3	ENSPTRP00000088336	ENSPTRP00000054732	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Neuronal acetylcholine receptor subunit beta-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.995
CHRNA4	CHRNB4	ENSPTRP00000088336	ENSPTRP00000012561	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Cholinergic receptor nicotinic beta 4 subunit.	0.994
CHRNA4	CHRNE	ENSPTRP00000088336	ENSPTRP00000014702	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Cholinergic receptor nicotinic epsilon subunit.	0.965
CHRNA4	CHRNG	ENSPTRP00000088336	ENSPTRP00000046107	Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.	Cholinergic receptor nicotinic gamma subunit.	0.965