TIAM1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	PAK1	ENSPTRP00000077648	ENSPTRP00000007058	Cell division cycle 42 (GTP binding protein, 25kDa).	Non-specific serine/threonine protein kinase.	0.997
CDC42	PARD3	ENSPTRP00000077648	ENSPTRP00000042389	Cell division cycle 42 (GTP binding protein, 25kDa).	PARD3 isoform 2.	0.955
CDC42	RAC1	ENSPTRP00000077648	ENSPTRP00000068561	Cell division cycle 42 (GTP binding protein, 25kDa).	Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).	0.986
CDC42	RAC2	ENSPTRP00000077648	ENSPTRP00000069135	Cell division cycle 42 (GTP binding protein, 25kDa).	Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2).	0.705
CDC42	RAC3	ENSPTRP00000077648	ENSPTRP00000024681	Cell division cycle 42 (GTP binding protein, 25kDa).	Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3).	0.735
CDC42	RAP1B	ENSPTRP00000077648	ENSPTRP00000070769	Cell division cycle 42 (GTP binding protein, 25kDa).	Ras-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family.	0.513
CDC42	TIAM1	ENSPTRP00000077648	ENSPTRP00000023836	Cell division cycle 42 (GTP binding protein, 25kDa).	T-cell lymphoma invasion and metastasis 1.	0.976
HRAS	KRAS	ENSPTRP00000005495	ENSPTRP00000084588	V-Ha-ras Harvey rat sarcoma viral oncogene homolog.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.997
HRAS	NRAS	ENSPTRP00000005495	ENSPTRP00000001956	V-Ha-ras Harvey rat sarcoma viral oncogene homolog.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.997
HRAS	TIAM1	ENSPTRP00000005495	ENSPTRP00000023836	V-Ha-ras Harvey rat sarcoma viral oncogene homolog.	T-cell lymphoma invasion and metastasis 1.	0.931
KRAS	HRAS	ENSPTRP00000084588	ENSPTRP00000005495	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	V-Ha-ras Harvey rat sarcoma viral oncogene homolog.	0.997
KRAS	NRAS	ENSPTRP00000084588	ENSPTRP00000001956	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.996
KRAS	TIAM1	ENSPTRP00000084588	ENSPTRP00000023836	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	T-cell lymphoma invasion and metastasis 1.	0.934
NRAS	HRAS	ENSPTRP00000001956	ENSPTRP00000005495	Neuroblastoma RAS viral (V-ras) oncogene homolog.	V-Ha-ras Harvey rat sarcoma viral oncogene homolog.	0.997
NRAS	KRAS	ENSPTRP00000001956	ENSPTRP00000084588	Neuroblastoma RAS viral (V-ras) oncogene homolog.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.996
NRAS	TIAM1	ENSPTRP00000001956	ENSPTRP00000023836	Neuroblastoma RAS viral (V-ras) oncogene homolog.	T-cell lymphoma invasion and metastasis 1.	0.923
PAK1	CDC42	ENSPTRP00000007058	ENSPTRP00000077648	Non-specific serine/threonine protein kinase.	Cell division cycle 42 (GTP binding protein, 25kDa).	0.997
PAK1	RAC1	ENSPTRP00000007058	ENSPTRP00000068561	Non-specific serine/threonine protein kinase.	Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).	0.988
PAK1	RAC2	ENSPTRP00000007058	ENSPTRP00000069135	Non-specific serine/threonine protein kinase.	Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2).	0.983
PAK1	RAC3	ENSPTRP00000007058	ENSPTRP00000024681	Non-specific serine/threonine protein kinase.	Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3).	0.982