ABCG1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC5	ABCG1	ENSPTRP00000079803	ENSPTRP00000092604	ATP-binding cassette, sub-family C (CFTR/MRP), member 5.	ABCG1 isoform 8.	0.614
ABCG1	ABCC5	ENSPTRP00000092604	ENSPTRP00000079803	ABCG1 isoform 8.	ATP-binding cassette, sub-family C (CFTR/MRP), member 5.	0.614
ABCG1	ABCG5	ENSPTRP00000092604	ENSPTRP00000020391	ABCG1 isoform 8.	ATP binding cassette subfamily G member 5.	0.755
ABCG1	APOE	ENSPTRP00000092604	ENSPTRP00000054411	ABCG1 isoform 8.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.682
ABCG1	CETP	ENSPTRP00000092604	ENSPTRP00000087924	ABCG1 isoform 8.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.631
ABCG1	LDLR	ENSPTRP00000092604	ENSPTRP00000075226	ABCG1 isoform 8.	LDLR isoform 7.	0.652
ABCG1	NPC1	ENSPTRP00000092604	ENSPTRP00000080513	ABCG1 isoform 8.	Niemann-Pick disease, type C1.	0.662
ABCG1	NR1H2	ENSPTRP00000092604	ENSPTRP00000019472	ABCG1 isoform 8.	Nuclear receptor subfamily 1, group H, member 2.	0.675
ABCG1	NR1H3	ENSPTRP00000092604	ENSPTRP00000079039	ABCG1 isoform 8.	Nuclear receptor subfamily 1 group H member 3.	0.710
ABCG1	SREBF2	ENSPTRP00000092604	ENSPTRP00000024869	ABCG1 isoform 8.	Sterol regulatory element binding transcription factor 2.	0.693
ABCG1	XPR1	ENSPTRP00000092604	ENSPTRP00000002909	ABCG1 isoform 8.	Xenotropic and polytropic retrovirus receptor 1.	0.651
ABCG5	ABCG1	ENSPTRP00000020391	ENSPTRP00000092604	ATP binding cassette subfamily G member 5.	ABCG1 isoform 8.	0.755
ABCG5	APOE	ENSPTRP00000020391	ENSPTRP00000054411	ATP binding cassette subfamily G member 5.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.486
ABCG5	CETP	ENSPTRP00000020391	ENSPTRP00000087924	ATP binding cassette subfamily G member 5.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.480
ABCG5	LDLR	ENSPTRP00000020391	ENSPTRP00000075226	ATP binding cassette subfamily G member 5.	LDLR isoform 7.	0.618
ABCG5	NPC1	ENSPTRP00000020391	ENSPTRP00000080513	ATP binding cassette subfamily G member 5.	Niemann-Pick disease, type C1.	0.563
ABCG5	NR1H2	ENSPTRP00000020391	ENSPTRP00000019472	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1, group H, member 2.	0.641
ABCG5	NR1H3	ENSPTRP00000020391	ENSPTRP00000079039	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1 group H member 3.	0.642
ABCG5	SREBF2	ENSPTRP00000020391	ENSPTRP00000024869	ATP binding cassette subfamily G member 5.	Sterol regulatory element binding transcription factor 2.	0.696
ABCG5	XPR1	ENSPTRP00000020391	ENSPTRP00000002909	ATP binding cassette subfamily G member 5.	Xenotropic and polytropic retrovirus receptor 1.	0.696