TMPRSS3 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMPRSS3

Transmembrane serine protease 3; Belongs to the peptidase S1 family. (453 aa)

Predicted Functional Partners:

UBASH3A

0.674

SLC26A4

0.668

UMODL1

0.647

OTOF

0.630

GJB2

0.630

PJVK

0.626

TMC1

0.618

MYO15A

0.584

MYO6

0.567

GJB6

0.565

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GJB2	GJB6	ENSPTRP00000082048	ENSPTRP00000041093	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.689
GJB2	MYO15A	ENSPTRP00000082048	ENSPTRP00000015079	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Myosin XVA.	0.700
GJB2	MYO6	ENSPTRP00000082048	ENSPTRP00000071251	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	MYO6 isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.571
GJB2	OTOF	ENSPTRP00000082048	ENSPTRP00000067285	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	OTOF isoform 1.	0.655
GJB2	PJVK	ENSPTRP00000082048	ENSPTRP00000049012	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	DFNB59 isoform 1.	0.611
GJB2	SLC26A4	ENSPTRP00000082048	ENSPTRP00000033528	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.940
GJB2	TMC1	ENSPTRP00000082048	ENSPTRP00000035938	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Transmembrane channel-like protein.	0.681
GJB2	TMPRSS3	ENSPTRP00000082048	ENSPTRP00000023992	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Transmembrane serine protease 3; Belongs to the peptidase S1 family.	0.630
GJB6	GJB2	ENSPTRP00000041093	ENSPTRP00000082048	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.689
GJB6	MYO15A	ENSPTRP00000041093	ENSPTRP00000015079	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Myosin XVA.	0.743
GJB6	MYO6	ENSPTRP00000041093	ENSPTRP00000071251	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	MYO6 isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.471
GJB6	OTOF	ENSPTRP00000041093	ENSPTRP00000067285	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	OTOF isoform 1.	0.551
GJB6	PJVK	ENSPTRP00000041093	ENSPTRP00000049012	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	DFNB59 isoform 1.	0.576
GJB6	SLC26A4	ENSPTRP00000041093	ENSPTRP00000033528	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.739
GJB6	TMC1	ENSPTRP00000041093	ENSPTRP00000035938	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Transmembrane channel-like protein.	0.479
GJB6	TMPRSS3	ENSPTRP00000041093	ENSPTRP00000023992	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Transmembrane serine protease 3; Belongs to the peptidase S1 family.	0.565
MYO15A	GJB2	ENSPTRP00000015079	ENSPTRP00000082048	Myosin XVA.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.700
MYO15A	GJB6	ENSPTRP00000015079	ENSPTRP00000041093	Myosin XVA.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.743
MYO15A	OTOF	ENSPTRP00000015079	ENSPTRP00000067285	Myosin XVA.	OTOF isoform 1.	0.785
MYO15A	PJVK	ENSPTRP00000015079	ENSPTRP00000049012	Myosin XVA.	DFNB59 isoform 1.	0.588