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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF2L1Stromal cell-derived factor 2-like 1. (221 aa)    
Predicted Functional Partners:
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 
 0.984
DNAJB11
DnaJ heat shock protein family (Hsp40) member B11.
   
 0.904
CRELD2
CRELD2 isoform 1.
   
 
 0.902
MANF
MANF isoform 1.
   
  
 0.866
HYOU1
Hypoxia up-regulated 1.
   
 0.815
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
   
 0.803
PREP
Prolyl endopeptidase.
      
 0.795
HSP90B1
Heat shock protein 90 beta family member 1.
   
 
 0.733
ENSPTRP00000089993
annotation not available
   
 
 0.733
PDIA4
Protein disulfide-isomerase A4.
   
 
 0.685
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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