STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)    
Predicted Functional Partners:
DHX15
DEAH (Asp-Glu-Ala-His) box polypeptide 15.
   
 0.996
SYF2
SYF2 homolog, RNA splicing factor.
    
  0.979
CDC40
Cell division cycle 40 homolog.
   
 0.971
GCFC2
GC-rich sequence DNA-binding factor 2.
    
 0.960
CWF19L2
CWF19 like cell cycle control factor 2.
    
 0.946
XAB2
XPA binding protein 2.
   
 0.926
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
  0.908
DHX32
DEAH (Asp-Glu-Ala-His) box polypeptide 32.
   
 0.886
DQX1
DEAQ-box RNA dependent ATPase 1.
   
 0.886
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
   
 
 0.882
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.