STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCC2Activating signal cointegrator 1 complex subunit 2. (757 aa)    
Predicted Functional Partners:
ASCC3
ASCC3 isoform 2.
    
 0.999
ASCC1
Activating signal cointegrator 1 complex subunit 1.
    
 0.996
TRIP4
Thyroid hormone receptor interactor 4.
    
 0.965
ALKBH3
AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase.
    
 0.900
HFM1
HFM1 isoform 1.
    
 0.862
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
  
 0.775
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.774
ZNF830
Zinc finger protein 830.
      
 0.758
KANSL2
KAT8 regulatory NSL complex subunit 2.
      
 0.758
PPM1F
PPM1F isoform 4.
      
 0.729
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.