STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; Belongs to the 14-3-3 family. (246 aa)    
Predicted Functional Partners:
BRAF
BRAF isoform 1; Belongs to the protein kinase superfamily.
   
 0.981
CDC25C
CDC25C isoform 7.
    
 0.979
ARAF
V-raf murine sarcoma 3611 viral oncogene homolog.
   
 0.979
CDC25B
Cell division cycle 25 homolog B.
    
 0.974
YAP1
Yes-associated protein 1.
    
 0.972
BAD
Bcl2-associated agonist of cell death.
    
 0.964
WWTR1
WW domain containing transcription regulator 1.
    
 0.946
FOXO3
FOXO3 isoform 1.
    
 0.944
RAF1
RAF1 isoform 2; Belongs to the protein kinase superfamily.
   
 0.912
CSNK1E
Casein kinase 1, epsilon; Belongs to the protein kinase superfamily.
    
 0.909
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.