STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
   
 0.979
MMP2
Matrix metallopeptidase 2.
   
 0.975
ADAM17
ADAM17 isoform 3.
    
 0.936
MMP14
Matrix metallopeptidase 14.
   
 0.776
MMP7
Matrix metallopeptidase 7.
   
 0.771
MMP3
Matrix metallopeptidase 3 (Stromelysin 1, progelatinase).
   
 0.749
EFEMP1
EGF-containing fibulin-like extracellular matrix protein 1.
   
  
 0.742
TIMP2
CEP295NL isoform 1.
   
 
0.706
MMP8
Matrix metallopeptidase 8.
   
 0.682
MMP1
Matrix metallopeptidase 1 (Interstitial collagenase).
   
 0.677
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.