Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PICK1Protein interacting with PRKCA 1. (416 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
    
 0.987
TSPAN7
Tetraspanin-7; May be involved in cell proliferation and cell motility; Belongs to the tetraspanin (TM4SF) family.
    
 0.947
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
    
 0.943
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
    
 0.938
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.910
NHSL2
NHSL2 isoform 4.
    
   0.910
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
    
 0.906
GRIP1
Glutamate receptor interacting protein 1.
    
 0.873
GRM7
Glutamate metabotropic receptor 7.
    
 
 0.846
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
   
 0.803
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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