STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICK1Protein interacting with PRKCA 1. (416 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
    
 0.990
TSPAN7
Tetraspanin-7; May be involved in cell proliferation and cell motility; Belongs to the tetraspanin (TM4SF) family.
     
 0.942
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
    
 0.912
GRIP1
Glutamate receptor interacting protein 1.
    
 0.904
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.898
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
    
 0.860
GRIP2
Glutamate receptor interacting protein 2.
   
 0.851
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
    
 0.820
GRM7
Glutamate metabotropic receptor 7.
    
 
 0.808
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
   
 0.760
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.