MCHR1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MCHR1

Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. (422 aa)

Predicted Functional Partners:

PMCH

0.991

MCHR2

0.929

ENSPTRP00000087048

0.918

PMCHL1

0.918

GNAI1

0.903

GNG2

0.885

GNB1

0.869

GNAI3

0.846

GNG4

0.833

GNAQ

0.828

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000087048	GNAI1	ENSPTRP00000087048	ENSPTRP00000071974	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.483
ENSPTRP00000087048	GNB1	ENSPTRP00000087048	ENSPTRP00000067330	annotation not available	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.514
ENSPTRP00000087048	GNG2	ENSPTRP00000087048	ENSPTRP00000065345	annotation not available	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.527
ENSPTRP00000087048	MCHR1	ENSPTRP00000087048	ENSPTRP00000024831	annotation not available	Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.	0.918
ENSPTRP00000087048	MCHR2	ENSPTRP00000087048	ENSPTRP00000031504	annotation not available	Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.885
GNAI1	ENSPTRP00000087048	ENSPTRP00000071974	ENSPTRP00000087048	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	annotation not available	0.483
GNAI1	GNAI3	ENSPTRP00000071974	ENSPTRP00000001821	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.999
GNAI1	GNAQ	ENSPTRP00000071974	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.683
GNAI1	GNB1	ENSPTRP00000071974	ENSPTRP00000067330	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.997
GNAI1	GNG2	ENSPTRP00000071974	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.992
GNAI1	GNG4	ENSPTRP00000071974	ENSPTRP00000003602	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.978
GNAI1	MCHR1	ENSPTRP00000071974	ENSPTRP00000024831	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.	0.903
GNAI1	MCHR2	ENSPTRP00000071974	ENSPTRP00000031504	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.735
GNAI1	PMCH	ENSPTRP00000071974	ENSPTRP00000009113	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Pro-MCH.	0.483
GNAI1	PMCHL1	ENSPTRP00000071974	ENSPTRP00000087079	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Pro-MCH variant; Belongs to the melanin-concentrating hormone family.	0.483
GNAI3	GNAI1	ENSPTRP00000001821	ENSPTRP00000071974	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.999
GNAI3	GNAQ	ENSPTRP00000001821	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.980
GNAI3	GNB1	ENSPTRP00000001821	ENSPTRP00000067330	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.997
GNAI3	GNG2	ENSPTRP00000001821	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.977
GNAI3	GNG4	ENSPTRP00000001821	ENSPTRP00000003602	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.987

page 1 of 5

Server load: low (28%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About