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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa)    
Predicted Functional Partners:
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.949
CANX
CANX isoform 1.
   
 
 0.930
EDEM3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
0.926
XBP1
XBP1 isoform 4.
     
 0.919
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
    
 
 0.918
EDEM2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
     
0.904
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
   
 
 0.792
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9.
    
 
 0.757
LOC107971755
dnaJ homolog subfamily B member 9.
    
 
 0.757
ATF6
Activating transcription factor 6.
   
  
 0.744
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.