node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN7L3 | KAT2A | ENSPTRP00000069746 | ENSPTRP00000015659 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Histone acetyltransferase KAT2A isoform X1. | 0.991 |
ATXN7L3 | KAT2B | ENSPTRP00000069746 | ENSPTRP00000025331 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.952 |
ATXN7L3 | SGF29 | ENSPTRP00000069746 | ENSPTRP00000013546 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | SGF29 isoform 6. | 0.991 |
ATXN7L3 | SUPT20H | ENSPTRP00000069746 | ENSPTRP00000071034 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | SPT20 homolog, SAGA complex component. | 0.993 |
ATXN7L3 | TADA2A | ENSPTRP00000069746 | ENSPTRP00000015434 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcriptional adapter. | 0.712 |
ATXN7L3 | TADA2B | ENSPTRP00000069746 | ENSPTRP00000027374 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcriptional adapter. | 0.992 |
ATXN7L3 | TADA3 | ENSPTRP00000069746 | ENSPTRP00000025171 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcriptional adaptor 3. | 0.991 |
ATXN7L3 | TAF10 | ENSPTRP00000069746 | ENSPTRP00000060099 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.987 |
ATXN7L3 | TAF9 | ENSPTRP00000069746 | ENSPTRP00000083849 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. | 0.989 |
ATXN7L3 | TRRAP | ENSPTRP00000069746 | ENSPTRP00000046739 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.992 |
KAT2A | ATXN7L3 | ENSPTRP00000015659 | ENSPTRP00000069746 | Histone acetyltransferase KAT2A isoform X1. | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] | 0.991 |
KAT2A | KAT2B | ENSPTRP00000015659 | ENSPTRP00000025331 | Histone acetyltransferase KAT2A isoform X1. | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.991 |
KAT2A | SGF29 | ENSPTRP00000015659 | ENSPTRP00000013546 | Histone acetyltransferase KAT2A isoform X1. | SGF29 isoform 6. | 0.998 |
KAT2A | SUPT20H | ENSPTRP00000015659 | ENSPTRP00000071034 | Histone acetyltransferase KAT2A isoform X1. | SPT20 homolog, SAGA complex component. | 0.993 |
KAT2A | TADA2A | ENSPTRP00000015659 | ENSPTRP00000015434 | Histone acetyltransferase KAT2A isoform X1. | Transcriptional adapter. | 0.988 |
KAT2A | TADA2B | ENSPTRP00000015659 | ENSPTRP00000027374 | Histone acetyltransferase KAT2A isoform X1. | Transcriptional adapter. | 0.988 |
KAT2A | TADA3 | ENSPTRP00000015659 | ENSPTRP00000025171 | Histone acetyltransferase KAT2A isoform X1. | Transcriptional adaptor 3. | 0.998 |
KAT2A | TAF10 | ENSPTRP00000015659 | ENSPTRP00000060099 | Histone acetyltransferase KAT2A isoform X1. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.993 |
KAT2A | TAF9 | ENSPTRP00000015659 | ENSPTRP00000083849 | Histone acetyltransferase KAT2A isoform X1. | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. | 0.997 |
KAT2A | TRRAP | ENSPTRP00000015659 | ENSPTRP00000046739 | Histone acetyltransferase KAT2A isoform X1. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.998 |