FANCD2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	FANCA	ENSPTRP00000009812	ENSPTRP00000014483	Breast cancer 2, early onset.	FANCA isoform 6.	0.723
BRCA2	FANCB	ENSPTRP00000009812	ENSPTRP00000037144	Breast cancer 2, early onset.	FANCB isoform 1.	0.718
BRCA2	FANCD2	ENSPTRP00000009812	ENSPTRP00000025203	Breast cancer 2, early onset.	FANCD2 isoform 1.	0.994
BRCA2	FANCE	ENSPTRP00000009812	ENSPTRP00000030890	Breast cancer 2, early onset.	Fanconi anemia, complementation group E.	0.720
BRCA2	FANCG	ENSPTRP00000009812	ENSPTRP00000035752	Breast cancer 2, early onset.	Fanconi anemia group G protein isoform X1.	0.933
BRCA2	FANCI	ENSPTRP00000009812	ENSPTRP00000012702	Breast cancer 2, early onset.	FANCI isoform 2.	0.923
BRCA2	FANCL	ENSPTRP00000009812	ENSPTRP00000020519	Breast cancer 2, early onset.	FA complementation group L.	0.692
BRCA2	FANCM	ENSPTRP00000009812	ENSPTRP00000010694	Breast cancer 2, early onset.	Fanconi anemia, complementation group M.	0.763
BRCA2	UBE2T	ENSPTRP00000009812	ENSPTRP00000003097	Breast cancer 2, early onset.	Ubiquitin-conjugating enzyme E2T (Putative); Belongs to the ubiquitin-conjugating enzyme family.	0.712
FAN1	FANCA	ENSPTRP00000011713	ENSPTRP00000014483	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FANCA isoform 6.	0.749
FAN1	FANCB	ENSPTRP00000011713	ENSPTRP00000037144	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FANCB isoform 1.	0.679
FAN1	FANCD2	ENSPTRP00000011713	ENSPTRP00000025203	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FANCD2 isoform 1.	0.993
FAN1	FANCE	ENSPTRP00000011713	ENSPTRP00000030890	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Fanconi anemia, complementation group E.	0.475
FAN1	FANCG	ENSPTRP00000011713	ENSPTRP00000035752	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Fanconi anemia group G protein isoform X1.	0.748
FAN1	FANCI	ENSPTRP00000011713	ENSPTRP00000012702	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FANCI isoform 2.	0.907
FAN1	FANCL	ENSPTRP00000011713	ENSPTRP00000020519	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group L.	0.757
FAN1	FANCM	ENSPTRP00000011713	ENSPTRP00000010694	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Fanconi anemia, complementation group M.	0.844
FAN1	UBE2T	ENSPTRP00000011713	ENSPTRP00000003097	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Ubiquitin-conjugating enzyme E2T (Putative); Belongs to the ubiquitin-conjugating enzyme family.	0.620
FANCA	BRCA2	ENSPTRP00000014483	ENSPTRP00000009812	FANCA isoform 6.	Breast cancer 2, early onset.	0.723
FANCA	FAN1	ENSPTRP00000014483	ENSPTRP00000011713	FANCA isoform 6.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.749