STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLH1MutL homolog 1, colon cancer, nonpolyposis type 2. (756 aa)    
Predicted Functional Partners:
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.999
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
PMS2
PMS1 homolog 2, mismatch repair system component.
    
0.999
CK820_G0052740
PMS2 isoform 6.
 
  
 0.997
MLH3
MLH3 isoform 1.
    
0.997
CK820_G0047513
Uncharacterized protein.
    
0.995
EXO1
EXO1 isoform 1.
   
 0.994
BLM
BLM isoform 1.
  
 0.994
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.994
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.