STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (2564 aa)    
Predicted Functional Partners:
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.955
H3-4
HIST3H3 isoform 1.
   
 0.952
LOC112209457-4
Histone H3.1.
   
 0.919
LOC471875
Histone H3.1-like.
   
 0.919
HTT
HTT isoform 1.
   
 0.887
H2BC21
HIST2H2BE isoform 1.
    
 0.855
H3C13
HIST2H3A isoform 1.
   
 0.852
LOC746430
Uncharacterized LOC746430.
   
 0.852
LOC107966300
Histone H3.
   
 0.852
HIST1H3A
H3F3B isoform 13.
   
 0.851
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.