| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGAP35 | RHOA | ENSPTRP00000075057 | ENSPTRP00000025759 | Glucocorticoid receptor DNA binding factor 1. | Ras homolog family member A. | 0.996 |
| ARHGAP35 | RHOC | ENSPTRP00000075057 | ENSPTRP00000071746 | Glucocorticoid receptor DNA binding factor 1. | Rho-related GTP-binding protein RhoC isoform X1. | 0.914 |
| ARHGAP35 | ROCK2 | ENSPTRP00000075057 | ENSPTRP00000063417 | Glucocorticoid receptor DNA binding factor 1. | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. | 0.412 |
| ARHGDIA | RHOA | ENSPTRP00000060458 | ENSPTRP00000025759 | Rho GDP dissociation inhibitor alpha. | Ras homolog family member A. | 0.997 |
| ARHGDIA | RHOC | ENSPTRP00000060458 | ENSPTRP00000071746 | Rho GDP dissociation inhibitor alpha. | Rho-related GTP-binding protein RhoC isoform X1. | 0.917 |
| ARHGEF1 | ARHGEF11 | ENSPTRP00000018955 | ENSPTRP00000091210 | Rho guanine nucleotide exchange factor 1. | Rho guanine nucleotide exchange factor (GEF) 11. | 0.943 |
| ARHGEF1 | ARHGEF12 | ENSPTRP00000018955 | ENSPTRP00000058269 | Rho guanine nucleotide exchange factor 1. | Rho guanine nucleotide exchange factor (GEF) 12. | 0.930 |
| ARHGEF1 | RHOA | ENSPTRP00000018955 | ENSPTRP00000025759 | Rho guanine nucleotide exchange factor 1. | Ras homolog family member A. | 0.995 |
| ARHGEF1 | RHOC | ENSPTRP00000018955 | ENSPTRP00000071746 | Rho guanine nucleotide exchange factor 1. | Rho-related GTP-binding protein RhoC isoform X1. | 0.889 |
| ARHGEF1 | ROCK1 | ENSPTRP00000018955 | ENSPTRP00000084841 | Rho guanine nucleotide exchange factor 1. | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] | 0.588 |
| ARHGEF1 | ROCK2 | ENSPTRP00000018955 | ENSPTRP00000063417 | Rho guanine nucleotide exchange factor 1. | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. | 0.627 |
| ARHGEF1 | SMURF1 | ENSPTRP00000018955 | ENSPTRP00000047812 | Rho guanine nucleotide exchange factor 1. | E3 ubiquitin-protein ligase. | 0.435 |
| ARHGEF11 | ARHGEF1 | ENSPTRP00000091210 | ENSPTRP00000018955 | Rho guanine nucleotide exchange factor (GEF) 11. | Rho guanine nucleotide exchange factor 1. | 0.943 |
| ARHGEF11 | ARHGEF12 | ENSPTRP00000091210 | ENSPTRP00000058269 | Rho guanine nucleotide exchange factor (GEF) 11. | Rho guanine nucleotide exchange factor (GEF) 12. | 0.939 |
| ARHGEF11 | RHOA | ENSPTRP00000091210 | ENSPTRP00000025759 | Rho guanine nucleotide exchange factor (GEF) 11. | Ras homolog family member A. | 0.997 |
| ARHGEF11 | RHOC | ENSPTRP00000091210 | ENSPTRP00000071746 | Rho guanine nucleotide exchange factor (GEF) 11. | Rho-related GTP-binding protein RhoC isoform X1. | 0.886 |
| ARHGEF11 | ROCK1 | ENSPTRP00000091210 | ENSPTRP00000084841 | Rho guanine nucleotide exchange factor (GEF) 11. | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] | 0.529 |
| ARHGEF11 | ROCK2 | ENSPTRP00000091210 | ENSPTRP00000063417 | Rho guanine nucleotide exchange factor (GEF) 11. | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. | 0.648 |
| ARHGEF12 | ARHGEF1 | ENSPTRP00000058269 | ENSPTRP00000018955 | Rho guanine nucleotide exchange factor (GEF) 12. | Rho guanine nucleotide exchange factor 1. | 0.930 |
| ARHGEF12 | ARHGEF11 | ENSPTRP00000058269 | ENSPTRP00000091210 | Rho guanine nucleotide exchange factor (GEF) 12. | Rho guanine nucleotide exchange factor (GEF) 11. | 0.939 |
