STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNAI2Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa)    
Predicted Functional Partners:
GNB1
Guanine nucleotide binding protein (G protein), beta polypeptide 1.
   
 0.997
GNAI3
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
  
 
0.992
ADORA1
Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
    
 0.984
GNAI1
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.
  
 
0.973
DRD2
D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
    
 0.965
RGS9
Regulator of G protein signaling 9.
   
 0.961
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.956
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
    
 0.954
LPAR1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.954
APLNR
APLNR isoform 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.953
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.