| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIFM1 | CPOX | ENSPTRP00000070055 | ENSPTRP00000026149 | Apoptosis-inducing factor, mitochondrion-associated, 1. | Coproporphyrinogen oxidase. | 0.627 |
| ALAD | CPOX | ENSPTRP00000065179 | ENSPTRP00000026149 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Coproporphyrinogen oxidase. | 0.789 |
| ALAD | ENDOV | ENSPTRP00000065179 | ENSPTRP00000070032 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | ENDOV isoform 5. | 0.676 |
| ALAD | FECH | ENSPTRP00000065179 | ENSPTRP00000063006 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.750 |
| ALAD | HMBS | ENSPTRP00000065179 | ENSPTRP00000007486 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Hydroxymethylbilane synthase. | 0.999 |
| ALAD | PPOX | ENSPTRP00000065179 | ENSPTRP00000081647 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.723 |
| ALAD | UROD | ENSPTRP00000065179 | ENSPTRP00000001156 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.890 |
| ALAD | UROS | ENSPTRP00000065179 | ENSPTRP00000005362 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen III synthase. | 0.986 |
| CPOX | AIFM1 | ENSPTRP00000026149 | ENSPTRP00000070055 | Coproporphyrinogen oxidase. | Apoptosis-inducing factor, mitochondrion-associated, 1. | 0.627 |
| CPOX | ALAD | ENSPTRP00000026149 | ENSPTRP00000065179 | Coproporphyrinogen oxidase. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.789 |
| CPOX | ENDOV | ENSPTRP00000026149 | ENSPTRP00000070032 | Coproporphyrinogen oxidase. | ENDOV isoform 5. | 0.911 |
| CPOX | FECH | ENSPTRP00000026149 | ENSPTRP00000063006 | Coproporphyrinogen oxidase. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.748 |
| CPOX | HMBS | ENSPTRP00000026149 | ENSPTRP00000007486 | Coproporphyrinogen oxidase. | Hydroxymethylbilane synthase. | 0.735 |
| CPOX | OGFOD1 | ENSPTRP00000026149 | ENSPTRP00000074523 | Coproporphyrinogen oxidase. | 2-oxoglutarate and iron-dependent oxygenase domain containing 1. | 0.698 |
| CPOX | PPOX | ENSPTRP00000026149 | ENSPTRP00000081647 | Coproporphyrinogen oxidase. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.996 |
| CPOX | TWNK | ENSPTRP00000026149 | ENSPTRP00000050357 | Coproporphyrinogen oxidase. | Twinkle mtDNA helicase. | 0.779 |
| CPOX | UROD | ENSPTRP00000026149 | ENSPTRP00000001156 | Coproporphyrinogen oxidase. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.995 |
| CPOX | UROS | ENSPTRP00000026149 | ENSPTRP00000005362 | Coproporphyrinogen oxidase. | Uroporphyrinogen III synthase. | 0.725 |
| ENDOV | ALAD | ENSPTRP00000070032 | ENSPTRP00000065179 | ENDOV isoform 5. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.676 |
| ENDOV | CPOX | ENSPTRP00000070032 | ENSPTRP00000026149 | ENDOV isoform 5. | Coproporphyrinogen oxidase. | 0.911 |
