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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM45ATransmembrane protein 45A. (291 aa)    
Predicted Functional Partners:
P4HA1
Prolyl 4-hydroxylase, alpha polypeptide I.
      
 0.542
PTP4A1
Protein tyrosine phosphatase type IVA protein 1.
      
 0.470
SETD3
Protein-histidine N-methyltransferase.
      
 0.444
DDIT4
DNA-damage-inducible transcript 4.
      
 0.434
LOC738449
Iron-sulfur cluster scaffold homolog; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
      
 0.425
ISCU
ISCU isoform 5; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
      
 0.425
BNIP3
BCL2 interacting protein 3.
      
 0.412
C5H5orf46
Chromosome 5 C5orf46 homolog.
   
  
 0.411
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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