STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGDHomogentisate 1,2-dioxygenase. (445 aa)    
Predicted Functional Partners:
HPD
4-hydroxyphenylpyruvate dioxygenase.
  
 0.997
GSTZ1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
 
 
 0.994
HPDL
4-hydroxyphenylpyruvate dioxygenase.
  
 0.957
HPS4
Hermansky-Pudlak syndrome 4.
  
 0.953
FAH
Fumarylacetoacetase.
  
 
 0.853
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
  
 0.828
F13B
Coagulation factor XIII B chain.
   
  
 0.825
CFHR5
CFHR5 isoform 1.
   
  
 0.764
PAH
Phenylalanine hydroxylase.
  
  
 0.749
TH
Tyrosine hydroxylase.
  
  
 0.745
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.