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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFSerotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor (P90, CD71).
  
 0.999
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
   
 0.727
MIS12
MIS12, MIND kinetochore complex component, homolog.
   
   0.727
ALB
ALB isoform 2.
   
  
 0.701
AHSG
Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family.
   
  
 0.680
TFR2
Transferrin receptor 2.
  
 0.674
A2M
Alpha-2-macroglobulin.
   
 
 0.674
ENSPTRP00000078404
annotation not available
  
 0.674
CP
CP isoform 1; Belongs to the multicopper oxidase family.
   
 
 0.672
SERPINA1
Serpin family A member 1; Belongs to the serpin family.
   
 0.656
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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