SIAH2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGLN1	EGLN2	ENSPTRP00000062173	ENSPTRP00000044177	EGLN1 isoform 1.	T0107007 isoform 1.	0.956
EGLN1	EGLN3	ENSPTRP00000062173	ENSPTRP00000010607	EGLN1 isoform 1.	Egl-9 family hypoxia inducible factor 3.	0.728
EGLN1	ENSPTRP00000092229	ENSPTRP00000062173	ENSPTRP00000092229	EGLN1 isoform 1.	annotation not available	0.570
EGLN1	SIAH1	ENSPTRP00000062173	ENSPTRP00000013820	EGLN1 isoform 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.466
EGLN1	SIAH2	ENSPTRP00000062173	ENSPTRP00000026742	EGLN1 isoform 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.727
EGLN2	EGLN1	ENSPTRP00000044177	ENSPTRP00000062173	T0107007 isoform 1.	EGLN1 isoform 1.	0.956
EGLN2	SIAH1	ENSPTRP00000044177	ENSPTRP00000013820	T0107007 isoform 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.566
EGLN2	SIAH2	ENSPTRP00000044177	ENSPTRP00000026742	T0107007 isoform 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.750
EGLN3	EGLN1	ENSPTRP00000010607	ENSPTRP00000062173	Egl-9 family hypoxia inducible factor 3.	EGLN1 isoform 1.	0.728
EGLN3	SIAH1	ENSPTRP00000010607	ENSPTRP00000013820	Egl-9 family hypoxia inducible factor 3.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.670
EGLN3	SIAH2	ENSPTRP00000010607	ENSPTRP00000026742	Egl-9 family hypoxia inducible factor 3.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.886
ENSPTRP00000061118	SIAH1	ENSPTRP00000061118	ENSPTRP00000013820	annotation not available	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.703
ENSPTRP00000061118	SIAH2	ENSPTRP00000061118	ENSPTRP00000026742	annotation not available	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.794
ENSPTRP00000092229	EGLN1	ENSPTRP00000092229	ENSPTRP00000062173	annotation not available	EGLN1 isoform 1.	0.570
ENSPTRP00000092229	SIAH1	ENSPTRP00000092229	ENSPTRP00000013820	annotation not available	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.566
ENSPTRP00000092229	SIAH2	ENSPTRP00000092229	ENSPTRP00000026742	annotation not available	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.750
HIPK2	SIAH1	ENSPTRP00000033846	ENSPTRP00000013820	Homeodomain interacting protein kinase 2.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.880
HIPK2	SIAH2	ENSPTRP00000033846	ENSPTRP00000026742	Homeodomain interacting protein kinase 2.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.760
SIAH1	EGLN1	ENSPTRP00000013820	ENSPTRP00000062173	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	EGLN1 isoform 1.	0.466
SIAH1	EGLN2	ENSPTRP00000013820	ENSPTRP00000044177	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	T0107007 isoform 1.	0.566