| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | CTPS1 | ENSPTRP00000083069 | ENSPTRP00000074876 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.765 |
| ALDH18A1 | EPRS1 | ENSPTRP00000083069 | ENSPTRP00000092889 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | EPRS isoform 1. | 0.818 |
| ALDH18A1 | GATB | ENSPTRP00000083069 | ENSPTRP00000028352 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.832 |
| ALDH18A1 | GMPS | ENSPTRP00000083069 | ENSPTRP00000026780 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Guanine monphosphate synthetase. | 0.922 |
| CTPS1 | ALDH18A1 | ENSPTRP00000074876 | ENSPTRP00000083069 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.765 |
| CTPS1 | ENSPTRP00000085877 | ENSPTRP00000074876 | ENSPTRP00000085877 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | annotation not available | 0.466 |
| CTPS1 | EPRS1 | ENSPTRP00000074876 | ENSPTRP00000092889 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | EPRS isoform 1. | 0.749 |
| CTPS1 | GATB | ENSPTRP00000074876 | ENSPTRP00000028352 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.622 |
| CTPS1 | GMPS | ENSPTRP00000074876 | ENSPTRP00000026780 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Guanine monphosphate synthetase. | 0.905 |
| CTPS1 | IMPDH1 | ENSPTRP00000074876 | ENSPTRP00000090298 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.466 |
| CTPS1 | IMPDH2 | ENSPTRP00000074876 | ENSPTRP00000041919 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.673 |
| CTPS1 | LOC465053 | ENSPTRP00000074876 | ENSPTRP00000089069 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 1-like. | 0.466 |
| CTPS1 | LOC467901 | ENSPTRP00000074876 | ENSPTRP00000072097 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine-5'-monophosphate dehydrogenase 1 pseudogene. | 0.466 |
| ENSPTRP00000085877 | CTPS1 | ENSPTRP00000085877 | ENSPTRP00000074876 | annotation not available | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.466 |
| ENSPTRP00000085877 | GMPS | ENSPTRP00000085877 | ENSPTRP00000026780 | annotation not available | Guanine monphosphate synthetase. | 0.896 |
| ENSPTRP00000085877 | IMPDH2 | ENSPTRP00000085877 | ENSPTRP00000041919 | annotation not available | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.814 |
| EPRS1 | ALDH18A1 | ENSPTRP00000092889 | ENSPTRP00000083069 | EPRS isoform 1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.818 |
| EPRS1 | CTPS1 | ENSPTRP00000092889 | ENSPTRP00000074876 | EPRS isoform 1. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.749 |
| EPRS1 | GATB | ENSPTRP00000092889 | ENSPTRP00000028352 | EPRS isoform 1. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.901 |
| EPRS1 | GMPS | ENSPTRP00000092889 | ENSPTRP00000026780 | EPRS isoform 1. | Guanine monphosphate synthetase. | 0.915 |
