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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCC1Methylcrotonoyl-CoA carboxylase 1 (Alpha). (725 aa)    
Predicted Functional Partners:
MCCC2
Methylcrotonoyl-CoA carboxylase 2 (Beta).
 
 0.998
IVD
Isovaleryl-CoA dehydrogenase.
  
 0.976
HADHA
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.941
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.941
PCCB
Propionyl-CoA carboxylase subunit beta.
 
 0.939
TTC14
Tetratricopeptide repeat domain 14.
   
  
 0.895
HLCS
Holocarboxylase synthetase (Biotin-(Proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase).
    
 0.881
DNAJC19
DnaJ heat shock protein family (Hsp40) member C19.
      
 0.859
NELFB
NELFB isoform 1.
   
 0.831
CLDN18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.782
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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