PARL protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MICU1	MICU2	ENSPTRP00000076550	ENSPTRP00000009713	Mitochondrial calcium uptake 1.	EF-hand domain family, member A1.	0.996
MICU1	NDUFA8	ENSPTRP00000076550	ENSPTRP00000036436	Mitochondrial calcium uptake 1.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.764
MICU1	NDUFB10	ENSPTRP00000076550	ENSPTRP00000013017	Mitochondrial calcium uptake 1.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.789
MICU1	NDUFB7	ENSPTRP00000076550	ENSPTRP00000018081	Mitochondrial calcium uptake 1.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.754
MICU1	PARL	ENSPTRP00000076550	ENSPTRP00000026963	Mitochondrial calcium uptake 1.	Androgen-induced gene 1 protein isoform X2.	0.798
MICU1	TIMM13	ENSPTRP00000076550	ENSPTRP00000017401	Mitochondrial calcium uptake 1.	Translocase of inner mitochondrial membrane 13 homolog; Belongs to the small Tim family.	0.833
MICU1	TIMM22	ENSPTRP00000076550	ENSPTRP00000014531	Mitochondrial calcium uptake 1.	Translocase of inner mitochondrial membrane 22 homolog.	0.758
MICU1	TIMM50	ENSPTRP00000076550	ENSPTRP00000018812	Mitochondrial calcium uptake 1.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.718
MICU2	MICU1	ENSPTRP00000009713	ENSPTRP00000076550	EF-hand domain family, member A1.	Mitochondrial calcium uptake 1.	0.996
MICU2	NDUFA8	ENSPTRP00000009713	ENSPTRP00000036436	EF-hand domain family, member A1.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.799
MICU2	NDUFB10	ENSPTRP00000009713	ENSPTRP00000013017	EF-hand domain family, member A1.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.763
MICU2	NDUFB7	ENSPTRP00000009713	ENSPTRP00000018081	EF-hand domain family, member A1.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.762
MICU2	PARL	ENSPTRP00000009713	ENSPTRP00000026963	EF-hand domain family, member A1.	Androgen-induced gene 1 protein isoform X2.	0.763
MICU2	TIMM13	ENSPTRP00000009713	ENSPTRP00000017401	EF-hand domain family, member A1.	Translocase of inner mitochondrial membrane 13 homolog; Belongs to the small Tim family.	0.860
MICU2	TIMM22	ENSPTRP00000009713	ENSPTRP00000014531	EF-hand domain family, member A1.	Translocase of inner mitochondrial membrane 22 homolog.	0.788
MICU2	TIMM50	ENSPTRP00000009713	ENSPTRP00000018812	EF-hand domain family, member A1.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.616
NDUFA8	MICU1	ENSPTRP00000036436	ENSPTRP00000076550	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Mitochondrial calcium uptake 1.	0.764
NDUFA8	MICU2	ENSPTRP00000036436	ENSPTRP00000009713	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	EF-hand domain family, member A1.	0.799
NDUFA8	NDUFB10	ENSPTRP00000036436	ENSPTRP00000013017	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999
NDUFA8	NDUFB7	ENSPTRP00000036436	ENSPTRP00000018081	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999