STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVL3Dishevelled segment polarity protein 3. (716 aa)    
Predicted Functional Partners:
DVL2
Dishevelled segment polarity protein 2.
  
 
0.987
VANGL2
Vang-like protein.
    
 0.984
FZD4
FZD4 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.983
VANGL1
Vang-like protein.
    
 0.980
FZD7
Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.979
AXIN2
AXIN2 isoform 1.
   
0.976
FZD6
Frizzled homolog 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.973
PRICKLE1
PRICKLE1 isoform 11.
    
 0.970
FZD5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.969
NKD1
NKD inhibitor of WNT signaling pathway 1.
    
 0.966
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (24%) [HD]