EIF4A2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EIF4A2

Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (408 aa)

Predicted Functional Partners:

EIF4A1

0.998

EIF4G1

0.998

EIF4G3

0.997

EIF4G2

0.990

PAIP1

0.983

EIF4E

0.972

PABPC1

0.953

EIF4B

0.947

PDCD4

0.946

LOC451932

0.890

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4A1	EIF4A2	ENSPTRP00000014825	ENSPTRP00000027042	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	0.998
EIF4A1	EIF4B	ENSPTRP00000014825	ENSPTRP00000093000	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic translation initiation factor 4B.	0.945
EIF4A1	EIF4E	ENSPTRP00000014825	ENSPTRP00000069083	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.992
EIF4A1	EIF4G1	ENSPTRP00000014825	ENSPTRP00000026995	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic translation initiation factor 4 gamma 1.	0.999
EIF4A1	EIF4G2	ENSPTRP00000014825	ENSPTRP00000005869	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Eukaryotic translation initiation factor 4 gamma 2.	0.997
EIF4A1	EIF4G3	ENSPTRP00000014825	ENSPTRP00000082033	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	EIF4G3 isoform 5.	0.999
EIF4A1	PABPC1	ENSPTRP00000014825	ENSPTRP00000069297	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.976
EIF4A1	PAIP1	ENSPTRP00000014825	ENSPTRP00000048224	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Poly(A) binding protein interacting protein 1.	0.985
EIF4A1	PDCD4	ENSPTRP00000014825	ENSPTRP00000080518	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	Programmed cell death 4 (Neoplastic transformation inhibitor).	0.995
EIF4A2	EIF4A1	ENSPTRP00000027042	ENSPTRP00000014825	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.998
EIF4A2	EIF4B	ENSPTRP00000027042	ENSPTRP00000093000	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4B.	0.947
EIF4A2	EIF4E	ENSPTRP00000027042	ENSPTRP00000069083	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.972
EIF4A2	EIF4G1	ENSPTRP00000027042	ENSPTRP00000026995	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 1.	0.998
EIF4A2	EIF4G2	ENSPTRP00000027042	ENSPTRP00000005869	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 2.	0.990
EIF4A2	EIF4G3	ENSPTRP00000027042	ENSPTRP00000082033	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	EIF4G3 isoform 5.	0.997
EIF4A2	LOC451932	ENSPTRP00000027042	ENSPTRP00000070288	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic initiation factor 4A-I pseudogene.	0.890
EIF4A2	PABPC1	ENSPTRP00000027042	ENSPTRP00000069297	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.953
EIF4A2	PAIP1	ENSPTRP00000027042	ENSPTRP00000048224	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Poly(A) binding protein interacting protein 1.	0.983
EIF4A2	PDCD4	ENSPTRP00000027042	ENSPTRP00000080518	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Programmed cell death 4 (Neoplastic transformation inhibitor).	0.946
EIF4B	EIF4A1	ENSPTRP00000093000	ENSPTRP00000014825	Eukaryotic translation initiation factor 4B.	Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.945