STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGS12Regulator of G-protein signaling 12. (1447 aa)    
Predicted Functional Partners:
GNAI1
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.
   
 0.851
GNAI3
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.846
GNB5
GNB5 isoform 1.
   
 0.736
GNAO1
G protein subunit alpha o1.
   
 0.700
GNA13
Guanine nucleotide binding protein (G protein), alpha 13.
   
 0.661
GNAQ
Guanine nucleotide binding protein (G protein), q polypeptide.
    
 0.619
GNA12
Guanine nucleotide binding protein (G protein) alpha 12.
   
 0.600
AKAP10
A kinase (PRKA) anchor protein 10.
   
  
 0.583
SUCLG2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.572
GNAI2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.
   
 0.563
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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