CD38 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD38	CD4	ENSPTRP00000027436	ENSPTRP00000054833	CD38 isoform 1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.957
CD38	ENPP1	ENSPTRP00000027436	ENSPTRP00000049619	CD38 isoform 1.	ENPP1 isoform 1.	0.937
CD38	ENPP3	ENSPTRP00000027436	ENSPTRP00000084211	CD38 isoform 1.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.937
CD38	NADK	ENSPTRP00000027436	ENSPTRP00000069692	CD38 isoform 1.	NADK isoform 3.	0.924
CD38	NMNAT2	ENSPTRP00000027436	ENSPTRP00000002942	CD38 isoform 1.	Nicotinamide nucleotide adenylyltransferase 2.	0.928
CD38	NMNAT3	ENSPTRP00000027436	ENSPTRP00000026629	CD38 isoform 1.	Nicotinamide-nucleotide adenylyltransferase.	0.929
CD38	SARM1	ENSPTRP00000027436	ENSPTRP00000015218	CD38 isoform 1.	Sterile alpha and TIR motif containing 1.	0.937
CD38	SIRT1	ENSPTRP00000027436	ENSPTRP00000004394	CD38 isoform 1.	SIRT1 isoform 2.	0.925
CD38	SIRT6	ENSPTRP00000027436	ENSPTRP00000017501	CD38 isoform 1.	SIRT6 isoform 1.	0.931
CD38	SIRT7	ENSPTRP00000027436	ENSPTRP00000016642	CD38 isoform 1.	SIRT7 isoform 2.	0.943
CD4	CD38	ENSPTRP00000054833	ENSPTRP00000027436	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CD38 isoform 1.	0.957
CD4	SIRT1	ENSPTRP00000054833	ENSPTRP00000004394	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	SIRT1 isoform 2.	0.506
ENPP1	CD38	ENSPTRP00000049619	ENSPTRP00000027436	ENPP1 isoform 1.	CD38 isoform 1.	0.937
ENPP1	ENPP3	ENSPTRP00000049619	ENSPTRP00000084211	ENPP1 isoform 1.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.919
ENPP1	NADK	ENSPTRP00000049619	ENSPTRP00000069692	ENPP1 isoform 1.	NADK isoform 3.	0.938
ENPP1	NMNAT2	ENSPTRP00000049619	ENSPTRP00000002942	ENPP1 isoform 1.	Nicotinamide nucleotide adenylyltransferase 2.	0.904
ENPP1	NMNAT3	ENSPTRP00000049619	ENSPTRP00000026629	ENPP1 isoform 1.	Nicotinamide-nucleotide adenylyltransferase.	0.904
ENPP1	SARM1	ENSPTRP00000049619	ENSPTRP00000015218	ENPP1 isoform 1.	Sterile alpha and TIR motif containing 1.	0.901
ENPP1	SIRT1	ENSPTRP00000049619	ENSPTRP00000004394	ENPP1 isoform 1.	SIRT1 isoform 2.	0.901
ENPP1	SIRT6	ENSPTRP00000049619	ENSPTRP00000017501	ENPP1 isoform 1.	SIRT6 isoform 1.	0.900