STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QDPRQuinoid dihydropteridine reductase. (244 aa)    
Predicted Functional Partners:
PCBD1
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
   
 
 0.982
PAH
Phenylalanine hydroxylase.
  
 
 0.977
SPR
Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase).
   
 0.968
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
   
 
 0.965
DHFR2
DHFR2 isoform 2.
   
 
 0.961
DHFR
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
   
 
 0.959
TPH1
Tryptophan hydroxylase 1.
  
 
 0.959
TPH2
Tryptophan hydroxylase 2.
  
 
 0.949
AKR1B1
Aldo-keto reductase family 1, member B1 (Aldose reductase).
  
 0.919
AKR1B10
AKR1B10 isoform 1.
  
 0.919
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.