| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKR1B1 | DHFR | ENSPTRP00000033770 | ENSPTRP00000029175 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.940 |
| AKR1B1 | DHFR2 | ENSPTRP00000033770 | ENSPTRP00000091206 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | DHFR2 isoform 2. | 0.944 |
| AKR1B1 | PAH | ENSPTRP00000033770 | ENSPTRP00000009118 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Phenylalanine hydroxylase. | 0.905 |
| AKR1B1 | QDPR | ENSPTRP00000033770 | ENSPTRP00000027445 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Quinoid dihydropteridine reductase. | 0.919 |
| AKR1B1 | SPR | ENSPTRP00000033770 | ENSPTRP00000074481 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase). | 0.950 |
| AKR1B1 | TH | ENSPTRP00000033770 | ENSPTRP00000005608 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Tyrosine hydroxylase. | 0.904 |
| AKR1B1 | TPH1 | ENSPTRP00000033770 | ENSPTRP00000078167 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Tryptophan hydroxylase 1. | 0.914 |
| AKR1B1 | TPH2 | ENSPTRP00000033770 | ENSPTRP00000088217 | Aldo-keto reductase family 1, member B1 (Aldose reductase). | Tryptophan hydroxylase 2. | 0.902 |
| DHFR | AKR1B1 | ENSPTRP00000029175 | ENSPTRP00000033770 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Aldo-keto reductase family 1, member B1 (Aldose reductase). | 0.940 |
| DHFR | DHFR2 | ENSPTRP00000029175 | ENSPTRP00000091206 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | DHFR2 isoform 2. | 0.972 |
| DHFR | PAH | ENSPTRP00000029175 | ENSPTRP00000009118 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Phenylalanine hydroxylase. | 0.914 |
| DHFR | QDPR | ENSPTRP00000029175 | ENSPTRP00000027445 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Quinoid dihydropteridine reductase. | 0.949 |
| DHFR | SPR | ENSPTRP00000029175 | ENSPTRP00000074481 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase). | 0.955 |
| DHFR | TH | ENSPTRP00000029175 | ENSPTRP00000005608 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Tyrosine hydroxylase. | 0.907 |
| DHFR | TPH1 | ENSPTRP00000029175 | ENSPTRP00000078167 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Tryptophan hydroxylase 1. | 0.911 |
| DHFR | TPH2 | ENSPTRP00000029175 | ENSPTRP00000088217 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Tryptophan hydroxylase 2. | 0.907 |
| DHFR2 | AKR1B1 | ENSPTRP00000091206 | ENSPTRP00000033770 | DHFR2 isoform 2. | Aldo-keto reductase family 1, member B1 (Aldose reductase). | 0.944 |
| DHFR2 | DHFR | ENSPTRP00000091206 | ENSPTRP00000029175 | DHFR2 isoform 2. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.972 |
| DHFR2 | PAH | ENSPTRP00000091206 | ENSPTRP00000009118 | DHFR2 isoform 2. | Phenylalanine hydroxylase. | 0.914 |
| DHFR2 | QDPR | ENSPTRP00000091206 | ENSPTRP00000027445 | DHFR2 isoform 2. | Quinoid dihydropteridine reductase. | 0.954 |
