CEP135 protein (Pan troglodytes) - STRING interaction network

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CEP135

Centrosomal protein 135kDa. (1140 aa)

Predicted Functional Partners:

ITSN2

0.978

SASS6

0.945

CENPJ

0.932

PLK1

0.912

STIL

0.886

PLK4

0.858

ITSN1

0.855

ITSN1-2

0.855

GAK

0.803

WRAP73

0.787

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPJ	CEP135	ENSPTRP00000009739	ENSPTRP00000027649	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	Centrosomal protein 135kDa.	0.932
CENPJ	GAK	ENSPTRP00000009739	ENSPTRP00000091059	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	Cyclin G associated kinase.	0.803
CENPJ	ITSN1	ENSPTRP00000009739	ENSPTRP00000083303	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	ITSN1 isoform 4.	0.855
CENPJ	ITSN1-2	ENSPTRP00000009739	ENSPTRP00000092097	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	ITSN1 isoform 7.	0.855
CENPJ	ITSN2	ENSPTRP00000009739	ENSPTRP00000020124	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	ITSN2 isoform 1.	0.978
CENPJ	PLK1	ENSPTRP00000009739	ENSPTRP00000093799	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	Serine/threonine-protein kinase PLK.	0.938
CENPJ	PLK4	ENSPTRP00000009739	ENSPTRP00000028220	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	Polo-like kinase 4.	0.922
CENPJ	SASS6	ENSPTRP00000009739	ENSPTRP00000001717	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	Spindle assembly 6 homolog.	0.952
CENPJ	STIL	ENSPTRP00000009739	ENSPTRP00000084476	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	STIL centriolar assembly protein.	0.960
CEP135	CENPJ	ENSPTRP00000027649	ENSPTRP00000009739	Centrosomal protein 135kDa.	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	0.932
CEP135	GAK	ENSPTRP00000027649	ENSPTRP00000091059	Centrosomal protein 135kDa.	Cyclin G associated kinase.	0.803
CEP135	ITSN1	ENSPTRP00000027649	ENSPTRP00000083303	Centrosomal protein 135kDa.	ITSN1 isoform 4.	0.855
CEP135	ITSN1-2	ENSPTRP00000027649	ENSPTRP00000092097	Centrosomal protein 135kDa.	ITSN1 isoform 7.	0.855
CEP135	ITSN2	ENSPTRP00000027649	ENSPTRP00000020124	Centrosomal protein 135kDa.	ITSN2 isoform 1.	0.978
CEP135	PLK1	ENSPTRP00000027649	ENSPTRP00000093799	Centrosomal protein 135kDa.	Serine/threonine-protein kinase PLK.	0.912
CEP135	PLK4	ENSPTRP00000027649	ENSPTRP00000028220	Centrosomal protein 135kDa.	Polo-like kinase 4.	0.858
CEP135	SASS6	ENSPTRP00000027649	ENSPTRP00000001717	Centrosomal protein 135kDa.	Spindle assembly 6 homolog.	0.945
CEP135	STIL	ENSPTRP00000027649	ENSPTRP00000084476	Centrosomal protein 135kDa.	STIL centriolar assembly protein.	0.886
CEP135	WRAP73	ENSPTRP00000027649	ENSPTRP00000000121	Centrosomal protein 135kDa.	WD repeat containing, antisense to TP73.	0.787
GAK	CENPJ	ENSPTRP00000091059	ENSPTRP00000009739	Cyclin G associated kinase.	Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...]	0.803