| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOX1 | CYP1A1 | ENSPTRP00000048899 | ENSPTRP00000058539 | Aldehyde oxidase 1. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.928 |
| AOX1 | CYP1A2 | ENSPTRP00000048899 | ENSPTRP00000070670 | Aldehyde oxidase 1. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.945 |
| AOX1 | CYP2A7 | ENSPTRP00000048899 | ENSPTRP00000018915 | Aldehyde oxidase 1. | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | 0.923 |
| AOX1 | CYP2D6 | ENSPTRP00000048899 | ENSPTRP00000042793 | Aldehyde oxidase 1. | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | 0.427 |
| AOX1 | CYP3A4 | ENSPTRP00000048899 | ENSPTRP00000081767 | Aldehyde oxidase 1. | Cytochrome P450 family 3 subfamily A member 4. | 0.943 |
| AOX1 | CYP3A5 | ENSPTRP00000048899 | ENSPTRP00000033296 | Aldehyde oxidase 1. | CYP3A5 isoform 1. | 0.927 |
| AOX1 | UGT2B10 | ENSPTRP00000048899 | ENSPTRP00000072985 | Aldehyde oxidase 1. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.943 |
| AOX1 | UGT2B7 | ENSPTRP00000048899 | ENSPTRP00000063599 | Aldehyde oxidase 1. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.944 |
| COMT | CYP1A1 | ENSPTRP00000024231 | ENSPTRP00000058539 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.952 |
| COMT | UGT2B10 | ENSPTRP00000024231 | ENSPTRP00000072985 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.919 |
| COMT | UGT2B7 | ENSPTRP00000024231 | ENSPTRP00000063599 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.935 |
| CYP1A1 | AOX1 | ENSPTRP00000058539 | ENSPTRP00000048899 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Aldehyde oxidase 1. | 0.928 |
| CYP1A1 | COMT | ENSPTRP00000058539 | ENSPTRP00000024231 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.952 |
| CYP1A1 | CYP1A2 | ENSPTRP00000058539 | ENSPTRP00000070670 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.924 |
| CYP1A1 | CYP2A7 | ENSPTRP00000058539 | ENSPTRP00000018915 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | 0.925 |
| CYP1A1 | CYP2D6 | ENSPTRP00000058539 | ENSPTRP00000042793 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | 0.934 |
| CYP1A1 | CYP2E1 | ENSPTRP00000058539 | ENSPTRP00000005465 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.940 |
| CYP1A1 | CYP3A4 | ENSPTRP00000058539 | ENSPTRP00000081767 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.958 |
| CYP1A1 | CYP3A5 | ENSPTRP00000058539 | ENSPTRP00000033296 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP3A5 isoform 1. | 0.952 |
| CYP1A1 | UGT2B10 | ENSPTRP00000058539 | ENSPTRP00000072985 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.933 |
