STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAAAN-acylethanolamine acid amidase; Belongs to the acid ceramidase family. (358 aa)    
Predicted Functional Partners:
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing.
      
 0.662
MGLL
Monoglyceride lipase.
    
 
 0.655
ACADSB
Acyl-CoA dehydrogenase, short/branched chain.
    
 
 0.652
FAAH
Fatty acid amide hydrolase.
    
 
 0.647
ALDH5A1
Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Belongs to the aldehyde dehydrogenase family.
      
 0.603
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
   
  
 0.590
LAMP2
Lysosomal associated membrane protein 2.
   
 
 0.589
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D.
      
 0.587
SQLE
Squalene epoxidase.
   
  
 0.581
VAC14
VAC14 component of PIKFYVE complex.
      
 0.575
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.