STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)    
Predicted Functional Partners:
CK820_G0054628
PKD1 isoform 4.
    
0.997
CK820_G0056924
NPIPA2 isoform 1.
 
  
 0.962
PKHD1
PKHD1 isoform 1.
      
 0.906
TRPC1
TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.884
TRPV4
Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.792
ADCY5
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.696
ENSPTRP00000066718
annotation not available
     
 0.693
EXOC5
Exocyst complex component 5.
     
 0.693
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
    
 
0.685
PRKCSH
Protein kinase C substrate 80K-H.
      
 0.674
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.