| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADH1A | ADH1B | ENSPTRP00000028008 | ENSPTRP00000071388 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | 0.987 |
| ADH1A | ALDH2 | ENSPTRP00000028008 | ENSPTRP00000090308 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | T0055793 isoform 1. | 0.883 |
| ADH1A | AOX1 | ENSPTRP00000028008 | ENSPTRP00000048899 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Aldehyde oxidase 1. | 0.914 |
| ADH1A | COMT | ENSPTRP00000028008 | ENSPTRP00000024231 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.916 |
| ADH1A | CYP26A1 | ENSPTRP00000028008 | ENSPTRP00000044339 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.914 |
| ADH1A | CYP2E1 | ENSPTRP00000028008 | ENSPTRP00000005465 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.936 |
| ADH1A | ESD | ENSPTRP00000028008 | ENSPTRP00000009965 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.913 |
| ADH1A | MAOA | ENSPTRP00000028008 | ENSPTRP00000037440 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Amine oxidase. | 0.917 |
| ADH1A | MAOB | ENSPTRP00000028008 | ENSPTRP00000037441 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Amine oxidase. | 0.919 |
| ADH1A | RETSAT | ENSPTRP00000028008 | ENSPTRP00000064116 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Retinol saturase (All-trans-retinol 13,14-reductase). | 0.910 |
| ADH1B | ADH1A | ENSPTRP00000071388 | ENSPTRP00000028008 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | 0.987 |
| ADH1B | ALDH2 | ENSPTRP00000071388 | ENSPTRP00000090308 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | T0055793 isoform 1. | 0.940 |
| ADH1B | AOX1 | ENSPTRP00000071388 | ENSPTRP00000048899 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Aldehyde oxidase 1. | 0.916 |
| ADH1B | COMT | ENSPTRP00000071388 | ENSPTRP00000024231 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.914 |
| ADH1B | CYP26A1 | ENSPTRP00000071388 | ENSPTRP00000044339 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.911 |
| ADH1B | CYP2E1 | ENSPTRP00000071388 | ENSPTRP00000005465 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.957 |
| ADH1B | ESD | ENSPTRP00000071388 | ENSPTRP00000009965 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.914 |
| ADH1B | MAOA | ENSPTRP00000071388 | ENSPTRP00000037440 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Amine oxidase. | 0.924 |
| ADH1B | MAOB | ENSPTRP00000071388 | ENSPTRP00000037441 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Amine oxidase. | 0.922 |
| ADH1B | RETSAT | ENSPTRP00000071388 | ENSPTRP00000064116 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Retinol saturase (All-trans-retinol 13,14-reductase). | 0.910 |
