| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| METTL1 | METTL2A | ENSPTRP00000008761 | ENSPTRP00000016131 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.556 |
| METTL1 | METTL6 | ENSPTRP00000008761 | ENSPTRP00000062653 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.410 |
| METTL1 | METTL8 | ENSPTRP00000008761 | ENSPTRP00000063580 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.478 |
| METTL1 | TRDMT1 | ENSPTRP00000008761 | ENSPTRP00000043696 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.845 |
| METTL1 | TRIT1 | ENSPTRP00000008761 | ENSPTRP00000001005 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.416 |
| METTL1 | TRMT10A | ENSPTRP00000008761 | ENSPTRP00000028013 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | RNA (Guanine-9-) methyltransferase domain containing 2. | 0.815 |
| METTL1 | TRMT11 | ENSPTRP00000008761 | ENSPTRP00000047047 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA methyltransferase 11 homolog. | 0.806 |
| METTL1 | TRMT2A | ENSPTRP00000008761 | ENSPTRP00000024244 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRM2 tRNA methyltransferase 2 homolog A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.487 |
| METTL1 | WDR4 | ENSPTRP00000008761 | ENSPTRP00000024006 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.999 |
| METTL2A | METTL1 | ENSPTRP00000016131 | ENSPTRP00000008761 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.556 |
| METTL2A | TRDMT1 | ENSPTRP00000016131 | ENSPTRP00000043696 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.481 |
| METTL2A | TRIT1 | ENSPTRP00000016131 | ENSPTRP00000001005 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.414 |
| METTL2A | TRMT10A | ENSPTRP00000016131 | ENSPTRP00000028013 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | RNA (Guanine-9-) methyltransferase domain containing 2. | 0.792 |
| METTL6 | METTL1 | ENSPTRP00000062653 | ENSPTRP00000008761 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.410 |
| METTL6 | METTL8 | ENSPTRP00000062653 | ENSPTRP00000063580 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.630 |
| METTL6 | TRDMT1 | ENSPTRP00000062653 | ENSPTRP00000043696 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.495 |
| METTL6 | TRMT10A | ENSPTRP00000062653 | ENSPTRP00000028013 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | RNA (Guanine-9-) methyltransferase domain containing 2. | 0.888 |
| METTL8 | METTL1 | ENSPTRP00000063580 | ENSPTRP00000008761 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.478 |
| METTL8 | METTL6 | ENSPTRP00000063580 | ENSPTRP00000062653 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.630 |
| METTL8 | TRDMT1 | ENSPTRP00000063580 | ENSPTRP00000043696 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.625 |
