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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBCKTBC1 domain containing kinase. (893 aa)    
Predicted Functional Partners:
C12H12orf4
Chromosome 12 open reading frame 4.
    
 
 0.689
MOSPD3
MOSPD3 isoform 6.
      
 0.571
MOSPD3-2
Motile sperm domain containing 3.
      
 0.571
PDCD2
Programmed cell death 2.
      
 0.502
IL6R
Interleukin 6 receptor.
    
   0.499
TBC1D22A
TBC1 domain family, member 22A.
      
0.421
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
    
 
 0.418
TCP10L
T-complex protein 10A homolog 1; May be involved in transcriptional regulation. Has in vitro transcription inhibition activity.
    
   0.414
NME6
Nucleoside diphosphate kinase.
   
  
 0.409
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.